The University Of Veterinary & Animal Sciences Swat
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Dr. Ajab Khan

Dr. Ajab Khan

Associate Professor (Head of Department)

Department:Department of Pathobiology
Specialization: PhD in Clinical Veterinary Medicine (Pathology)
Onboard Status: Available
Work Experience & Appointments
Associate Professor (Head of Department)
University of Veterinary & Animal Sciences, Swat
(2023 - Present)
• Teaching, academic research, and departmental responsibilities.
Academic Qualifications
Ph.D / Master / Bachelor
Recognized University / HEC (Graduated) – 1st Division / Merit
Research Papers
1. Ajab Khan, Kuohai F, Na S, Wei Y, Yaogui S, Panpan S, Ali RJ, Hongquan L, Recombinant porcine NKlysin inhibits the invasion of hepatocellular carcinoma cells in vitro. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2019, 140: 1249-59 https://DOI.ORG/10.1016/J.IJBIOMAC.2019.08.212 (IF= 8.025)

2. Ajab Khan, Wei Yin, Sun Na, Yaogui Sun, Panpan Sun, Anam Ahsan, Ali Raza Jahejo, Hongquan Li, Kuohai Fan. Recombinant porcine NK-Lysin inhibits Fascin1 expression by regulating MAPK pathway [J]. Bio Med Research international (Under Review)

3. Ajab Khan, Khohai fan, Li Hongquan. Advanced strategies to inhibit Fascin1, a metastatic biomarker (Review article). [J]. Biomedica. Vol 35, Issue 2, Jun-Apr 2019.

4. Kuohai Fan Wenjuan Du, Zhirui Wang, Ajab Khan, Hongquan Li, Junbing Jiang. Anti-Invasion and Anti-Metastatic Effects of Porcine Recombinant NK-lysin on SMMC-7721 Human Hepatocellular Carcinoma cells [J]. Bio Med Research international, 2019, https://doi.org/10.1155/2019/5318729 (IF: 3.246)

5. Kuohai Fan, Yina An, Zhirui Wang, Wei Yin, Sun Na, Yaogui Sun, Ajab Khan, Hongquan Li. Antibacterial Activity of Recombinant Porcine β-defensin 2 [J]. Pakistan Veterinary Journal, 39: 3, DOI: 10.29261/pakvetj/2019.030 (IF: 1.803)

6. Sun Panpan, Sun Na, Yin Wei, Sun Yaogui, Fan Kuohai, Guo Jianhua, Khan Ajab, He Yongming, Li Hongquan. Matrine inhibits IL-1β secretion in primary porcine alveolar macrophages through MyD88/NF-κB pathway and NLRP3 inflammasome. Veterinary research. 2019. 50(1); 53. doi.org/10.1186/s13567-019-0671-x (IF: 4.269)

7. Sun Na*, Sun Panpan*, Yao Mingjie, Khan Ajab, Sun Yaogui, Fan Kuohai, Yin Wei, Li Hongquan. Autophagy involved in antiviral activity of Sodium tanshinone IIA sulfonate against porcine reproductive and respiratory syndrome virus (PRRSV) infection in vitro [J]. Antiviral therapy, 2019, 24(1): 27-33. Doi: 10.3851/MP3268 (IF: 2.088)

8. Sun Na*, Sun Panpan*, Xie Ni, Khan Ajab, Sun Yaogui, Fan Kuohai, Yin Wei and Li Hongquan. Antiviral and immunomodulatory effects of dipotassium glycyrrhizinate in chicks artificially infected with infectious bursal disease virus [J]. Pakistan Veterinary Journal. 2018. 39(1): 43-48. DOI: 10.29261/pakvetj/2018.109 (IF: 1.803)

9. Yan Feng, Lei Wang, Ajab Khan, Rui zhao, Siang Wei and Xiaoyuan Jing. Fermented wheat bran by xylanaseproducing Bacillus cereus boosts the intestinal microflora of broiler chickens [J]. Poultry Science. 2019. Aug: 2019. doi.org/10.3382/ps/pez482 (IF: 4.014)

10. Jiangang Zheng, Yinlan Xu, Ajab Khan, Shaoyu Wang, Hongquan Li and Na Sun. In-vitro Screening of Traditional Chinese Medicines Compounds Derived with Anti-encephalomyocarditis virus Activites [J]. Biotechnology and Bioprocess Engineering DOI: 10.1007/s12257-019-0354-5 (IF : 3.386)

11. YanYan Yi, ShuangXiu Wan, YaXin Hou, Jia Cheng, JianHua Guo, Shaoyu Wang, Ajab Khan, Na Sun, Hongquan Li. Chlorogenic acid rescues zearalenone induced injury to mouse ovarian granulosa cells [J]. Ecotoxicology and Environmental Safety doi.org/10.1016/j.ecoenv.2020.110401 (IF : 7.129)

12. Sun Na*, Hua Zhang, Sun Panpan, Khan Ajab, Jianhua Guo, Xiazhong Zheng, Sun Yaogui, Fan Kuohai, Yin Wei and Li Hongquan. Matrine exhibits antiviral activity in a PRRSV/PCV2 co-infected mouse model [J]. Phytomedicine. doi.org/10.1016/j.phymed.2020.153289 (IF: 6.656)

13. Li Zhang, Yanting Dong, Wenzhuo Wang, Taoran Zhao, Tingjuan Huang, Ajab Khan, Lei Wang, Zhizhen Li, Jun Xie and Bo Niu. Ethionine Suppresses Mitochondria Autophagy and Induces Apoptosis via Activation of Reactive Oxygen Species in Neural Tube Defects [J]. Frontiers in Neurology 2020. doi: 10.3389/fneur.2020.00242 (IF : 4.003)

14. Bin Du, Xuexian Liu, Ajab Khan, Shuangxiu Wan, Xiang Guo, Jixuan Xue, Ruiwen Fan* miRNA-183∼96∼182 regulates melanogenesis, cell proliferation and migration in B16 cells [J]. Acta Histochemica https://doi.org/10.1016/j.acthis.2020.151508 (IF : 2.479)

15. Ali Raza Jahejo, Sheng Niu, Ding Zhang, Guan Bao Ning, Afrasyab Khan, Raza Mangi, Muhammad Farhan Qadir, Ajab Khan, Jian-Hui Li and Wen-Xia Tian. Transcriptome analysis of MAPK signaling pathway and associated genes to angiogenesis in chicken erythrocytes on response to thiram induced tibial lesions [J]. Research in Veterinary Sciences 2019. doi.org/10.1016/j.rvsc.2019.10.013 (IF: 2.554)

16. Sansan Jia, Li Zhang, Kaili Zhang, Lei Wang, Ajab Khan, Juan Zhang, Yuqing Sun, Yufei Wang, Meiyan Song, Yi Lyu, Meining Li, Xin Lu, Bo Niu, Zhizhen Liu, and Jun Xie. Nkx2.1 downregulation is involved in brain abnormality induced by excess retinoic acid [J]. Acta Biochimica et Biophysica Sinica doi.org/10.1093/abbs/gmaa037 (IF : 3.848)

17. Xiao-Ling Wang, Lei Wang, Chao-Lu Hasi, Yu-Po Wang, Ajab Khan, Bin-Zhi Ren, Zhi, Zhen Liu, Shun-Lin, Hou, LiHong Yang, Liao-Yun Zhang, Yong-Kang Dong, Jun Xu, Jun Xie A rapid colloidal gold immunochromatographic assay for the diagnosis of coronavirus disease 2019. [J]. Chinese Medical Journal doi: 10.1097/CM9.0000000000000922 (IF : 6.133)

18. Ali Raza Jahejo, Ding Zhang, Sheng Niu, Raza Mangi, Afrasyab Khan, Muhammad Farhan Qadir, Ajab Khan, Huanchun Chen and Wen-Xia Tian. Transcriptome-based screening of intracellular pathways and angiogenesis related genes at different stages of thiram induced tibial lesions in broiler chickens [J]. BMC Genomics (IF : 4.56)

19. Ali Raza Jahejo, Nasir rajput, Jam Kashif, Dildar Hussain Kalhoro, Sheng Niu, Meng-li Qiao, Ding Zhang, Muhammad Farhan Qadir, Raza Mangi, Afrasyab Khan, Anam Ahsan, Ajab Khan and Wen-Xia Tian. Recombinant glutathione-Stransferase A3 protein regulates the angiogenesis-related genes of erythrocytes in thiram induced tibial lesions [J]. Research in Veterinary Science (IF : 2.554)

20. Ali Raza jahejo, Fa-jie Jia, Syed haider abbas raza, Mujahid Ali Shah, Jiao jiao Yin, Anam Ahsan, Muhammad Waqas, Sheng niu, Guan-bao Ning, Ding Zhang, Ajab Khan, Wen-xia Tian. Screening of Toll-like receptor signaling pathwayrelated genes and the response of recombinant glutathione S-transferase A3 protein to thiram induced apoptosis in chicken erythrocytes [J]. Developmental and Comparative Immunology. doi.org/10.1016/j.dci.2020.103831(IF:3.636)

21. Amjad Khan*, Muhammad Hassan Mushtaq, Mansur ud Din Ahmad, Abid Hussain, Asghar Khan, Ajab Khan and Habibun Nabi. INCIDENCE OF REPEAT BREEDING IN VARYING BREEDS OF BUFFALOES AND CATTLE IN DIFFERENT CLIMATIC CONDITIONS IN KHYBER PAKHTUNKHWA (PAKISTAN [J]. Buffalo Bulletin (IF : 0.27).

22. Li Zhang1,2, Dandan Li1, Juan Zhang1, Ping Yan1, Xueqin Liu1, Lei Wang1, Ajab Khan1, Zhizhen Liu1, Jianbing Mu3, Jun Xu2, Bo Niu1,4,*, and Jun Xie1,*. Excessive apoptosis and ROS induced by ethionine affect neural cell viability and differentiation [J]. Acta Biochimica et Biophysica Sinica (IF : 3.848)

23. Na Sun, Yutong Zhang, Yaxin Hou, Yanyan Yi, Jianhua Guo, Xiaozhong Zheng, Panpan Sun, Yaogui Sun, Ajab Khan and Hongquan Li* “Effects of Osthole on Progesterone Secretion in Chicken Preovulatory Follicles Granulosa Cells” [J]. Animals (IF: 2.752).

24. Jin Zhao, Shuangxiu Wan, Na Sun, Panpan Sun, Yaogui Sun, Ajab Khan, Jianhua Guo, Xiaozhong Zheng, Kuohai Fan, Wei Yin and Hongquan Li “Damage to intestinal barrier integrity in piglets caused by porcine reproductive and respiratory syndrome virus infection” [J]. Veterinary Research (IF: 3.829).

25. Qiao H, Zhang H, Khan Ajab, Li B, Ge L, Liu Y, Bian W, Liu Z, Xie J. Synthesis of cationic carbon dots and their effects on human serum proteins and in vitro blood coagulation. Luminescence. 2021 Nov;36(7):1671-83. https://doi.org/10.1002/bio.4108 (IF:2.163)

26. Yu-Hui Hao1,2, Zhi-Zhen Liu1 , Hong Zhao1 , Lei Wang1 , Ajab Khan1 , Jian-Bin Mu3 , Yu-Fei Wang1 , Li-Hong Yang1 , Ran Zhou4 , Jun Xie1 “Identification and characterization of murine adipose tissue-derived somatic stem cells of Shenque acupoint” [J]. Chinese Medical Journal. 2021 Nov 20;134(22):2730. Chinese Medical Journal 2021;134(22) (IF: 6.133)

27. Li Zhang1,2,3, Rui Cao1,4, Dandan Li1 , Yuqing Sun2,3, Juan Zhang1 , Xiuwei Wang5 , Ajab Khan1 , Zhizhen Liu1 , Bo Niu1* , Jun Xu2,3* and Jun Xie1* “Ethionine mediated reduction of S-adenosylmethionine is responsible for the neural tube defects in the development of mouse embryo-mediated m6A modification and is involved in neural tube defects via modulating Wnt/B-catenin signalling pathway” [J]. Epigenetics & Chromatin. 2021 Dec;14(1):1- 7.https://doi.org/10.1186/s13072-021-00426-3 (IF: 5.465)

28. Hua Zhang1†, Zhigang Cao1†, Panpan Sun1,2, Ajab Khan1 , Jianhua Guo3 , Yaogui Sun1 , Xiuju Yu1 , Kuohai Fan1,2, Wei Yin1 , E Li4 , Na Sun1 and Hongquan Li1* “A novel strategy for optimal component formula of anti-PRRSV fromnatural compounds using tandem mass tag labeled proteomic analyses” [J]. BMC Veterinary Research. 2022. https://doi.org/10.1186/s12917-022-03184-w (IF: 3.008)

29. Hejie Wang1 · Minmin Dou1 · Jun Li1 · PengCao1 · JunlingLi1 · Tianyan Guo1 · DipengZhao1 · AjabKhan1 · YingliangLi1 Baojun Li1 · RongDu1 · Jian Qin1,2 “Expression patterns andcorrelation analyses of muscle-specifc genes inthe process of sheep myoblast differentiation” [J]. In Vitro Cellular & Developmental Biology-Animal(2022): 1-12. l https://doi.org/10.1007/s11626-022-00721-7 (IF: 2.723)

30. Shuangxiu Wan, Na Sun, Hongquan Li, Ajab Khan, Xiaozhong Zheng, Yaogui Sun & Ruiwen Fan “Deoxynivalenol damages the intestinal barrier and biota of the broiler chickens” [J]. BMC Veterinary Research, 15 Aug 2022. https://doi.org/10.1186/s12917-022-03392-4 (IF: 3.008)

31. Qiu Zhong,1 Yaogui Sun,1 Ajab Khan,2 Jianhua Guo,3 Zhirui Wang,4 Na Sun,1 and Hongquan Li. ” 4,7-Didehydroneophysalin B Protects Rat Lung Epithelial Cells against Hydrogen Peroxide-Induced Oxidative Damage through Nrf2-Mediated Signaling Pathway” [J]. Oxidative Medicine and Cellular Longevity. 2022, https://doi.org/10.1155/2022/4189083. (IF: 7.310)

32. Jiangang Zheng1†, Panpan Sun2†, Na Sun1 , Zhili Hao3 , Kuohai Fan2 , Wei Yin1 , Ajab Khan4 , Jianhua Guo5 , Xiaozhong Zheng6 and Hongquan Li1* “Curcumol inhibits EMCV replication by activating CH25H andinhibiting the formation of ROs”[J] BMC Veterinry Research 2022. https://doi.org/10.1186/s12917-022-03531-x I

Book Chapters Published
• Ajab khan, Anam Ahsan, Muhammad A Farooq, Muhammad Navved and Hongquan Li. Role of polycyclic aromatic hydrocarbons as EDCs in Metabolic disorders. In endocrine disrupting chemicals induced metabolic disorders and treatment strategies [J]. Springer, pp 323-341 https://doi.org/10.1007/978-3-030-45923-9_19

• Anam Ahsan, Ajab Khan, Muhammad Asim Farooq, Muhammad Naveed, Mirza Muhammad Faran Ashraf Baig an d Wen xia Tian. Pyhsiology of Endocrine system and related metabolic disorders. In endocrine disrupting chemicals induced metabolic disorders and treatment strategies [J].Springer , pp 3-41. https://doi.org/10.1007/978-3-030-45923-9_1

• Ajab Khan, Aanam Ahsan, Muhammad Asim Farooq, Mirza Muhammad Farhan Ashraf Baig and Qurat-ul-ain Aslam. Stability Studies of Vaccines. In drug stability and chemical kinetics [J]. Springer, pp 167-185. https://link.springer.com/chapter/10.1007/978-981-15-6426-0_12

• Ajab Khan, Ali Raza Jahejo, Emerging environmental contaminants and drug metabolizing enzymes [J]. Biochemistry of Drug Metabolizing Enzymes. Academic Press, 2022. 109-124. https://www.sciencedirect.com/science/article/pii/B9780323951203000099

Courses Taught

Projects

Conferences/Seminars

• International Training workshop on Traditional Chinese veterinary medicine and techniques from July 10th 2017 to July 29th 2017 at Lanzhou institute of Husbandry and Pharmaceutical Sciences of CAAS.

• Attended 2nd and 3rd international livestock, dairy and poultry conference as an organizer at Expo centre Lahore.

• Attended International Halal Meat conference at Expo centre Lahore

• Attended Ist and 2nd International workshop of Dairy science Park (DSP) in Agriculture University Peshawar.